Disease-information

Pityriasis versicolor (PV) also known as tinea versicolor, which is chronic and superficial fungal skin disease caused by Malassezia yeasts. A permanent cure may difficult to achieve and this may explain the long-term nature of the disease. Consequently, a preventive treatment regimen may help to prevent the recurrence of pityriasis versicolor....
ADA: Diabetes Journals: Published June 2023Diabetes mellitus (DM) is one of the most important causes of CKD. Moreover, both DM and CKD are important risk factors for cardiovascular disease (CVD). Metformin is still the first-line drug for DM management. The concern, of course, is an increased risk of metformin-associated lactic acidosis (MALA)...
Thyroid disease can be broadly categorised as thyroid dysfunction (hypothyroidism, hyperthyroidism) and structural disease (goitre, nodules and cancer). Management is often straightforward, but there are pitfalls that may lead to misdiagnosis, overdiagnosis and inappropriate treatment. This article reviews the approach to common thyroid proble...
Journal of the European Academy of Dermatology and Venereology: JEADV: Published: May 2023Atopic dermatitis (AD) is the most common recurrent chronic inflammation in the skin in both children and adults. It is characterized by an itchy rash with typical localization and often requires daily treatment with emollients and/or topical corticosteroi...
Lippincott Williams & Wilkins (LWW): Hepatology Journal: Published on May, 2023This new American Association for the Study of Liver Diseases (AASLD) Guidance document reflects many advances in the field pertinent to any practitioner caring for patients with NAFLD and emphasizes advances in noninvasive risk stratification and therapeutics.The mo...
Hypothyroidism is a common endocrine disorder resulting from deficiency of thyroid hormone. Iodine deficiency remains the most common cause of hypothyroidism worldwide.The most common symptoms in adults are fatigue, lethargy, cold intolerance, weight gain, constipation, depression, change in voice, and dry skin, but clinical presentation can di...
The Journal of Urology:Clomipramine is a tricyclic antidepressant (TCA) that has been found effective at a daily dose of 25 mg or 50 mg for premature ejaculation (PE) in multiple studies. Additionally, TCAs can carry significant side effects such as dizziness, dry mouth, and constipation. As a result, on-demand treatment is greatly preferred, e...
Dengue is the most common mosquito-borne, viral disease in the world. Dengue virus is a single stranded positive polarity RNA virus, belongs to the family Flaviviridae. The Den-2 and Den-3 variants of dengue are active this year and of the two, Den-2 is more prominent, according to the Institute of Epidemiology, Disease Control and Researc...
The British Journal of DermatologyDermatophytic infections have undergone unprecedented changes in India in the recent past. Oral antifungal drugs are considered to have a high cure rate in tinea corporis, tinea cruris and tinea faciei.Clinical trials to find out the effectiveness of the four main oral antifungal drugs are lacking.Authors teste...
JAMA Network: November, 2019Proton pump inhibitors (PPIs) are drugs widely prescribed to reduce gastric acidity. Although they are considered globally safe, observational studies have reported significant adverse effects associated with their long-term use, such as osteoporotic-related fractures, vitamin B12 deficiency, kidney disease, or...
Superficial fungal infections are primarily caused by dermatophytes, Candida spp, and Malassezia species affects 20%–25% of the world’s population.The lesion of dermatophytosis is present with an annular or ring-shaped red scaly plaque with central clearing, often associated with severe pruritus.Systemic or topical antifungal drugs are used as...
JAMA Internal Medicine: Published on May, 2023Diabetic kidney disease is the leading cause of chronic kidney disease and end-stage kidney failure in the vast majority of the world. TAKE-HOME MESSAGEThis randomized clinical trial evaluated the use of glucose-lowering medications on kidney outcomes. A total of 5047 patients with type 2 diabet...