Disease-information
Introduction
Parkinson’s disease (PD) is a
neurodegenerative disease resulting from progressive death of the dopaminergic
neurons in the brainstem, particularly the substantia nigra pars compacta
(SNc). Besides the hallmark motor symptoms (hypokinesia, rest tremor, rigidity,
and postural instability), PD patients have non-motor symptoms...
Progesterone maintains pregnancy by
enhancing uterine quiescence. During early pregnancy, the syncytiotrophoblast
secretes human chorionic gonadotropin (hCG), which stimulates progesterone
production in the corpus luteum by preventing regression of this tissue.
Low serum hCG or progesterone
levels may predict first trimester abortions....
Treatment guidelines for type 2
diabetes mellitus (T2DM) recommend initiating pharmacotherapy with an oral
antidiabetic drug (OAD) to reduce hyperglycaemia when diet and exercise are
inadequate.
International guidelines recommend
metformin as the first OAD, whereas Japanese guidelines recognize that other
OADs may be more appropriate i...
Metabolic Syndrome and Related
Disorders Journal: Published
Online: 15 Feb 2022
Seborrheic dermatitis (SD) is a
common, chronic inflammatory disease with relapses and remissions.
TAKE HOME MESSAGE:
This study aimed to evaluate
metabolic syndrome (MS) and glucose metabolism disorders in patients with SD.
The study results showed...
The management of gastroesophageal
reflux disease (GERD) has been revolutionized with the development of proton
pump inhibitors (PPIs). Unfortunately, due to the inherent pharmacokinetic and
pharmacodynamic profiles of conventional PPIs, many patients continue to suffer
from symptoms related to GERD despite appropriate use of PPIs.
Curr...
JAMA: The Journal of the American Medical Association: Published
on April 5, 2022
Epilepsy affects approximately 65
million people worldwide. Persistent seizures are associated with a 20% to 40%
risk of bodily injuries (eg, fractures, burns, concussions) over 12-month
follow-up. The primary goal of epilepsy treatment is to eliminate seiz...
International Journal of Basic & Clinical Pharmacology: Published on July
2021
Superficial Tinea corporis is said
to be recurrent when there is recurrence of the disease within 6 weeks after
the completion of treatment. The prevalence of superficial mycosis is on the
rise with change in spectrum of infection and isolation of some uncommo...
Diabetes Care: American Diabetes Association Journal
The standard pharmacotherapy for
management of type 2 diabetes mellitus (T2DM) involves initiation with
monotherapy (usually metformin) unless there are contraindications or
intolerance, followed by sequential addition of other single agents, when
target glycaemic control is not achieved o...
The New England Journal
of Medicine (NEJM): Published
on July 15, 2021
The incidence rate of a single unprovoked seizure among
adults is 23 to 61 cases per 100,000 person-years.
After a first unprovoked seizure, the overall risk of
recurrence may be as high as 60%, and this risk is highest within the first 2
years.
Epilepsy is...
The New England Journal of Medicine
(NEJM):
Endometriosis is defined as the
presence of endometrium-like tissue outside the uterus.
Figure 1. Endometriosis
across the Life Course.
Endometriosis is primarily diagnosed
through surgical visualization — ideally, laparoscopy. Treatment consists of
surgical removal of lesions and hormon...
American Journal of Dermatology and Venereology: Published: Feb. 26, 2021
Dermatophytic infections are the
most common fungal infections affecting 20%–25% population globally. The hot
and humid climate in the tropical and subtropical countries like Bangladesh
makes Dermatophytosis is very common fungal infection.
Terbinafine is considered...
The American Diabetes Association
(ADA) “Standards of Medical Care in Diabetes” includes the ADA’s current
clinical practice recommendations and is intended to provide the components of
diabetes care, general treatment goals and guidelines, and tools to evaluate
quality of care.
Atherosclerotic cardiovascular
disease (ASCVD)—defined as...
