Practice-updates
Diabetes Research and
Clinical Practice: Published
on July, 2022The American Diabetes Association recommends that metformin
should be started at the time of type 2 diabetes mellitus (T2DM) diagnosis,
unless there are contraindications. Metformin is safe, effective, economic,
and might reduce the risk of cardiovascular events and death. When gl...
American College of Obstetricians and Gynecologists (ACOG):
Endometriosis is a chronic, estrogen-dependent
condition that causes dysmenorrhea and pelvic pain that affects 6–10% of women
of reproductive age.
Elagolix is an oral, nonpeptide Gonadotropin-releasing
hormone (GnRH) antagonist suppressed estradiol production in a dose-depend...
Hypertension is one of the leading
public health challenges worldwide. It is common in both developed and
developing countries.
Essential hypertension is believed
to be a result of complex interaction of genetic and environmental factors.
Increased peripheral resistance is responsible for most of the cases of
essential hypertension....
GERD is associated with substantial
reductions in subjective well-being, lower work productivity, and increased
healthcare use. The GERD in the Asia Pacific Survey (GAPS) found that GERD had
a negative impact on well-being for 94% of respondents in terms of stress (68%
of respondents), restrictions to daily activities (50%), and reduced wor...
Global Journal of Reproductive Medicine:
Endometriosis is a common disease in up to 10% of women of reproductive
age. It often causes symptoms such as dysmenorrhea, chronic pelvic pain,
dyspareunia and dyschezia. It is also associated with ovarian endometrioma
which requires surgery for both diagnosis and treatment. However, recurrence
r...
Threatened miscarriage is the most common complication in the
first half of pregnancy affecting 20-25% of women. Diagnosis of threatened
miscarriage is established when there is a viable pregnancy with vaginal
bleeding and a closed cervix.
Any woman who presents with threatened miscarriage;
ultrasound imaging is performed to ascertain th...
ADA Diabetes Care Journal:
Metformin
is the recommended first-line pharmacotherapy for patients with type 2 diabetes,
but most patients will ultimately require additional therapies to maintain
glycemic control.
Maintaining
intensive glucose control early in the disease process may lead to legacy
benefits that persist beyond the per...
PubMed Central: Published: July, 2021
Urticaria is a frequent, mast cell–driven disease that
presents with wheals, angioedema, or both. The lifetime prevalence for acute
urticaria is approximately 20%.
Chronic idiopathic urticaria (CIU) is a common skin condition
characterized by the appearance of recurrent wheals and/or angioede...
Treatment guidelines for type 2
diabetes mellitus (T2DM) recommend initiating pharmacotherapy with an oral
antidiabetic drug (OAD) to reduce hyperglycaemia when diet and exercise are
inadequate.
International guidelines recommend
metformin as the first OAD, whereas Japanese guidelines recognize that other
OADs may be more appropriate i...
The management of gastroesophageal
reflux disease (GERD) has been revolutionized with the development of proton
pump inhibitors (PPIs). Unfortunately, due to the inherent pharmacokinetic and
pharmacodynamic profiles of conventional PPIs, many patients continue to suffer
from symptoms related to GERD despite appropriate use of PPIs.
Curr...
JAMA: The Journal of the American Medical Association: Published
on April 5, 2022
Epilepsy affects approximately 65
million people worldwide. Persistent seizures are associated with a 20% to 40%
risk of bodily injuries (eg, fractures, burns, concussions) over 12-month
follow-up. The primary goal of epilepsy treatment is to eliminate seiz...
Diabetes Care: American Diabetes Association Journal
The standard pharmacotherapy for
management of type 2 diabetes mellitus (T2DM) involves initiation with
monotherapy (usually metformin) unless there are contraindications or
intolerance, followed by sequential addition of other single agents, when
target glycaemic control is not achieved o...
